84-1100-18　EB3 (EB1 Protein Family Member 3, End-binding Protein 3) 100ug　E0999-01A

特徴

• EB3 is a 282 amino acid homologue of EB1, a protein known to bind APC (adenomatous polyposis coli).
• It has been shown to bind to tubulin in vitro and microtubules in vivo.
• Northern blotting shows expressions to be mainly in brain, and to a lesser degree in muscle.
• EB3 interacts with APCL, a homologue of the tumor suppressor APC, and this interaction may be involved in the stabilization or extension of microtubules.
• Applications:Suitable for use in Western Blot.
• Other applications not tested.
• Recommended Dilution:Western Blot: 0.5-2ug/ml, in human brain, a ~38kD band is observedOptimal dilutions to be determined by the researcher.
• Positive Control:Human Brain Whole Tissue Lysate (Adult Whole Normal)
• Storage and Stability:May be stored at 4°C for short-term only.
• Aliquot to avoid repeated freezing and thawing.
• Store at -20°C.
• Aliquots are stable for 12 months after receipt.
• For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.