This gene may play a role in the development and normal function of the ovaries.
Mutations of this gene have been linked to premature ovarian failure.
Alternative splicing results in two protein isoforms.
Furthermore, each splice variant undergoes additional splicing in the 3' UTR.
Overall 4 splice variants have been described.
Applications:Suitable for use in Western Blot.
Other applications not tested.
Recommended Dilutions:Western Blot: 1:1000-1:10,000Optimal dilutions to be determined by the researcher.
Storage and Stability:May be stored at 4°C.
For long-term storage, aliquot and store at 4°C.
Do not freeze.
Aliquots are stable for 12 months after receipt.
For maximum recovery of product, centrifuge the original vial prior to removing the cap.
Further dilutions can be made in assay buffer.
仕様
Size：100ug
Host：rabbit
Source Antibody：human
Grade：Affinity Purified
Purity：Purified by immunoaffinity chromatography.
Form：Supplied as a liquid in Tris-citrate/phosphate pH 7.5, 0.09% sodium azide.
Specificity：Recognizes human Diaphanous 2 at ~125kD. Epitope: maps region between aa50-100. Reactivity with mouse Dia2 is unlikely owing to divergence of homolog.
Isotype：IgG
Calc Applications Abbrev：WB
Calc Crossreactivity：Hu
Immunogen：Synthetic peptide corresponding to a portion of human diaphanous homolog 2 encoded within exon 3 (Accession NP_006720).
