Derlin-1 is a channel-like protein, found in the ER membrane, responsible for degrading and funneling misfolded proteins and other cellular debris into the appropriate degradative pathways within the cell.
Cellular Localization: Subcellular localization in the endoplasmic reticulum
Positive Control: KRM (canine microsome) lysates.
(BD offers commercial liver microsomes)
Applications:Suitable for use in Western Blot and Immunohistochemistry.
Other applications not tested.
Recommended Dilution:Optimal dilutions to be determined by the researcher.
Storage and Stability:May be stored at 4°C for short-term only.
For long-term storage and to avoid repeated freezing and thawing, aliquot Store at -20°C.
Aliquots are stable for at least 12 months at -20°C.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Further dilutions can be made in assay buffer.
仕様
Size：100ul
Host：rabbit
Source Antibody：human
Grade：Affinity Purified
Purity：Purified by immunoaffinity chromatography.
Form：As reported
Specificity：This antibody is specific for Derlin-1. Species Crossreactivity: This antibody reacts with human and canine Derlin-1. No other specie has been tested. The immunogen used for this antibody production has 100% homology with human, Xenopus, bovine, and mouse protein.
Isotype：IgG
Calc Applications Abbrev：IHC WB
Calc Crossreactivity：Ca Hu
Immunogen：A synthetic peptide made to the C-terminal region of the human Derlin-1 protein sequence (between residues 200-251).
