84-1099-93　CTR1 (copper transporter 1, COPT1, hCTR1, solute carrier family 31 (copper transporters) member 1, SLC31A1) 100ul　C7948-17

特徴

• The trace metal copper (Cu) plays a crucial role in mammalian cells as a cofactor for many enzymes.
• Cu-related genetic diseases, such as Menkes disease and Wilson disease, arise from a lack of Cu homeostasis in mammalian cells.
• CTR1 is a high-affinity copper-uptake protein.
• The C-terminal domain is similar to the Raf family of protein kinases, but it's first two-thirds encodes a novel protein domain.
• CTR1 provides the primary avenue for copper uptake in mammalian cells, thereby, affecting Cu homeostasis and embryonic development.
• Positive Control: Human breast cancer and kidney tissue
• Applications:Suitable for use in Western Blot and Immunohistochemistry.
• Other applications not tested.
• Recommended Dilution:Western Blot: 1:1000Immunohistochemistry (paraffin): 1:250Optimal dilutions to be determined by the researcher.
• Storage and Stability:May be stored at 4°C.
• For long-term storage, aliquot and store at 4°C.
• Do not freeze.
• Aliquots are stable for 12 months.
• For maximum recovery of product, centrifuge the original vial prior to removing the cap.
• Further dilutions can be made in assay buffer.