c-Fos is a nuclear phosphoprotein which forms a tight but non-covalently linked complex with the JUN/AP-1 transcription factor.
It has a critical function in regulating the development of cells destined to form and maintain the skeleton.
It is thought to have an important role in signal transduction, cell proliferation and differentiation.
c-Fos expression increases upon a variety of stimuli, including growth factors, cytokines, neurotransmitters, polypeptide hormones, stress and cell injury.
Belongs to the bZIP family.
Fos subfamily.
Applications:Suitable for use in ELISA.
Other applications not tested.
Recommended Dilution:Optimal dilutions to be determined by the researcher.
Subcellular Localization: Nucleus.
Storage and Stability:May be stored at 4°C for short-term only.
For long-term storage and to avoid repeated freezing and thawing, aliquot Store at -20°C.
Aliquots are stable for at least 12 months at -20°C.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Further dilutions can be made in assay buffer.
仕様
Size：500ug
Host：sheep
Source Antibody：human
Grade：Affinity Purified
Purity：Purified by affinity chromatography.
Form：Supplied as a lyophilized powder. Reconstitute in 500 ul of sterile water. Centrifuge to remove any insoluble material.
Specificity：Recognizes c-fos. Species Crossreactivity: rat, rabbit, and hamster. Peptide Sequence Homology: human, mouse, rat, hamster and cat
Isotype：IgG
Calc Applications Abbrev：E
Calc Crossreactivity：Hm Hu Rb Rt
Immunogen：Synthetic peptide (MFSGFNADYEASSSRC; aa 2-17) conjugated to diphtheria toxoid
