84-1099-18 [受注停止]Adrenergic Receptor, beta 2 (B2AR) 50ug A0906-88B
特徴
- This protein is beta-2-adrenergic receptor which is a member of the G protein-coupled receptor superfamily.
- This receptor is directly associated with one of its ultimate effectors, the class C L-type calcium channel Ca(V)1.2.
- This receptor-channel complex also contains a G protein, an adenylyl cyclase, cAMP-dependent kinase, and the counterbalancing phosphatase, PP2A.
- The assembly of the signaling complex provides a mechanism that ensures specific and rapid signaling by this G protein-coupled receptor.
- This protein contains no introns in either its coding or untranslated sequences.
- Different polymorphic forms, point mutations, and/or downregulation of this gene are associated with nocturnal asthma, obesity and type 2 diabetes.
- Applications:Suitable for use in Western Blot.
- Other applications not tested.
- Recommended Dilutions:Western Blot: 1:500Optimal dilutions to be determined by the researcher.
- Recommended Secondary Antibodies:I1906-10: IgY, Chicken (HRP) Rb x Ch I1906-12: IgY, Chicken (FITC) Rb x Ch I1906-14: IgY, Chicken (AP) Rb x Ch
- Storage and Stability:May be stored at 4°C for short-term only.
- Aliquot to avoid repeated freezing and thawing.
- Store at -20°C.
- Aliquots are stable for 12 months after receipt.
- For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
- Size:50ug
- Host:chicken
- Source Antibody:human
- Grade:Affinity Purified
- Purity:Purified by affinity chromatography.
- Form:Supplied as a liquid in PBS, pH 7.4, 0.02% sodium azide.
- Specificity:Recognizes human Beta 2 Andrenergic Receptor at ~46.5kD.
- Isotype:IgY
- Calc Applications Abbrev:WB
- Calc Crossreactivity:Hu
- Immunogen:Recombinant protein corresponding to aa335-408, DFRIAFQELLC LRRSSLKAYGN GYSSNGNTGE QSGYHVEQEKE NKLLCEDLPGT EDFVGHQGTVP SDNIDSQGRNCS T, of human beta 2 Adrenergic Receptor. Cellular Localization: Cell Membrane
- Shelf Life:1year
- Swiss Prot Number:P07550
- EU Commodity Code:30021010
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