The Ah Receptor belongs to a family of proteins comprised of its dimerization partner ARNT (HIF-1 Beta) and the Drosophila proteins PER and SIM.
All of these proteins share an N-terminal sequence of ~200 amino acids termed the PAS domain.
This receptor, found in a variety of tissues, binds to a specific DNA enhancer sequence and initiates transcription of the mRNA for the cytochrome P-450 (CYPIA1) gene.
Positive Control: Mouse liver cytosol
Applications:Suitable for use in Western Blot.
Other applications not tested.
Recommended Dilution:Optimal dilutions to be determined by the researcher.
Storage and Stability:May be stored at 4°C for short-term only.
For long-term storage and to avoid repeated freezing and thawing, aliquot Store at -20°C.
Aliquots are stable for at least 12 months at -20°C.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Further dilutions can be made in assay buffer.
仕様
Size:100ul
Host:rabbit
Source Antibody:human
Grade:Affinity Purified
Purity:Purified by immunoaffinity chromatography.
Form:Tris-citrate/phosphate buffer, pH 7-8
Specificity:This antibody is specific for AHR. Species Crossreactivity: Recognizes mouse AHR. Other species have not been tested.
Isotype:IgG
Calc Applications Abbrev:WB
Calc Crossreactivity:Mo
Immunogen:Bacterially expressed human AHR (C-terminus).