Apoptotic events such as chromatin condensation and nuclear fragmentation are triggered by the activation of a family of cysteine proteases called caspases.
A novel protein, Acinus, indices apoptotic chromatin condensation after cleavage by caspase-3 without inducing DNA fragmentation and is essential for apoptotic chromatin condensation.
Applications:Suitable for use in Western Blot.
Other applications not tested.
Recommended Dilution:Western Blot: 1:500-1:1,000.
Optimal dilutions to be determined by the researcher.
Storage and Stability:May be stored at 4°C for short-term only.
For long-term storage and to avoid repeated freezing and thawing, aliquot Store at -20°C.
Aliquots are stable for at least 12 months at -20°C.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Further dilutions can be made in assay buffer.
仕様
Size:100ug
Host:rabbit
Source Antibody:human
Grade:Purified
Purity:Purified
Form:PBS with 0.02% sodium azide
Specificity:Reacts with the C-terminus of Acinus. Species Crossreactivity: Human. Other species have not been tested.
Isotype:IgG
Calc Applications Abbrev:WB
Calc Crossreactivity:Hu
Immunogen:A peptide made to the C-terminal sequence RNRQLEREKRREHS.