84-1098-46　［取扱停止］Bonzo, NT2 (STRL33, TYMSTR, G-Protein-coupled Receptor) 100ug　B2555-01

特徴

• Human immunodeficiency virus (HIV) and simian immunodeficiency virus (SIV) require coreceptors, in addition to CD4, to infect target cells.
• Some G protein-coupled receptors including CCR5, CXCR4, CCR3, and CCR2b in the chemokine receptor family have been identified as HIV coreceptors.
• An orphan G protein-coupled receptor was recently cloned and designated Bonzo, STRL33 and TYMSTR, and identified as HIV and SIV coreceptor (1-4).
• Bonzo/STRL33 serves as coreceptor for SIV, HIV-2 and HIV-1.
• The messenger RNA of Bonzo/STRL33 is expressed in lymphoid tissues and activated peripheral blood lymphocytes.
• Application(s):Suitable for use in Western blot.
• Recommended Dilution: 1:500
• Positive Control: Human spleen tissue lysate
• Storage and Stability:May be stored at 4°C for short-term only.
• For long-term storage and to avoid repeated freezing and thawing, add sterile glycerol (40-50%), aliquot and store at -20°C or colder.
• Aliquots are stable for at least 12 months at -20°C.
• For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
• Further dilutions can be made in assay buffer.