84-1097-96　Neurexin 1b 100ug　N2110-04

特徴

• Neurexin 1 beta is an 80kD member of the Neurexin family of proteins.
• It is expressed on neuronal presynaptic membranes and contributes to synapse formation through binding to postsynaptic neuroligins.
• An alternate start site in the Neurexin 1 gene generate an a- (long) and B- (short) isoform.
• Mature rat Neurexin 1B is a type I transmembrane glycoprotein that is 468 amino acids (aa) in length.
• It has a 346 aa extracellular region (aa 47-392) that contains one laminin-like G domain (aa 91-264).
• Within the G domain, the presence or absence of a splice site (aa 201-230) materially impacts neuroligin binding.
• Over aa 47-392, rat Neurexin 1B is 100% and 98% aa identical to mouse and human Neurexin 1B, respectively.
• Applications:Suitable for use in Direct ELISA and Western Blot.
• Other applications not tested.
• Recommended Dilution:Diretc ELISA: 0.5-1.0ug/ml detection limit for rrNeurexin 1Beta is ~ 0.5ng/well
• Western Blot: 1.0ug/mlOptimal dilutions to be determined by the researcher.
• Storage and Stability:Lyophilized powder may be stored at -20°C.
• Reconstitute to nominal volume by adding sterile 40-50% glycerol, aliquot and store at -20°C.
• Reconstituted product is stable for 12 months at -20°C.
• For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
• Further dilutions can be made in assay buffer.