84-1097-85 ISLR2 (Immunoglobulin Superfamily Containing Leucine-Rich Repeat 2, SST273) 100ug I8782-60
特徴
- ISLR-2 (Ig-superfamily containing LRR protein 2; also KIAA1465) is a 100-110kD member of the LRR family of proteins.
- It is expressed on developing motor, sensory and interneurons.
- Mature human ISLR-2 is 727aa in length.
- It is a type I transmembrane glycoprotein that contains a 571 aa extracellular domain (ECD) and a 135 aa cytoplasmic region.
- The ECD shows multiple LRRs (aa50-227) and one Ig-like domain (aa233-371).
- One alternate splice form may exist that shows a deletion of aa160-570.
- Over aa20-590, human ISLR-2 is 89% aa identical to both canine and mouse ISLR-2.
- Applications:Suitable for use in Direct ELISA and Western Blot.
- Other applications not tested.
- Recommended Dilutions:Western Blot: 0.1ug/ml using Recombinant Human ISLR‑2Optimal dilutions to be determined by the researcher.
- Storage and Stability:Lyophilized and reconstituted products are stable for 12 months after receipt at -20°C.
- Reconstitute with sterile PBS.
- Aliquot to avoid repeated freezing and thawing.
- Store at -20°C.
- For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
- Further dilutions can be made in assay buffer.
仕様
- Size:100ug
- Host:sheep
- Source Antibody:human
- Grade:Affinity Purified
- Purity:Purified by affinity chromatography.
- Form:Supplied as a lyophilized powder from PBS, 5% trehalose. Reconstitute with 500ul sterile PBS.
- Specificity:Recognizes human ISLR-2. ~25% cross-reactivity with recombinant human ISLR-2
- Isotype:IgG
- Calc Applications Abbrev:E WB
- Calc Crossreactivity:Hu
- Immunogen:Recombinant protein corresponding to Cys20-Leu590 at the extracellular domain of human ISLR-2, expressed in NS0 cells.
- Shelf Life:1year
- Swiss Prot Number:Q6UXK2
- EU Commodity Code:30021010
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