Transient receptor potential A1 (TRPA1) is an excitatory cation channel that is highly expressed in nociceptive neurons and plays an important role in inflammatory pain.
TRPA1 mediates the response to the proalgesic bradykinin as well as to pungent irritants found in mustards, garlic, and cinnamon.
TRPA1 may also be involved in hearing (as the mammalian hair cell mechanotransducer) and in the detection of cold stimuli.
Applications:Suitable for use in Immunohistochemistry.
Other applications not tested.
Recommended Dilution:Immunohistochemistry (Paraffin): 10-20ug/ml Requires antigen retrieval using heat treatment for 20 minutes prior to staining of paraffin sections.
0.01M sodium citrate buffer, pH 6.0 is recommended for this purpose
Optimal dilutions to be determined by the researcher.
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for 12 months after receipt.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size：50ug
Host：rabbit
Source Antibody：human
Grade：Affinity Purified
Purity：Purified by immunoaffinity chromatography.
Form：Supplied as a liquid in PBS, 0.09% sodium azide.
Specificity：Recognizes Human Transient Receptor Potential Cation Channel, Subfamily A, Member 1 (TRPA1).
Isotype：IgG
Calc Applications Abbrev：IHC
Calc Crossreactivity：Hu
Immunogen：Synthetic peptide corresponding to the internal domain of human TRPA1 (KLH).
