TGFb1 (Transforming Growth Factor-beta1) is a family of multifunctional 25kD proteins.
TGFb1 was originally identified for its ability to induce the growth of normal rodent fibroblasts in soft agar.
It is now known that TGFb1 is a potent growth inhibitor of many normal and transformed cell lines.
It regulates normal cell growth, development and tissue remodeling following injury.
TGFb1 is produced as latent high molecular weight complexes.
The activation of latent TGFb1 is an important step in the regulation of its action.
Applications:Suitable for use in ELISA, Immunofluorescence, Western Blot and Immunohistochemistry.
Other applications have not been tested.
Recommended Dilutions: ELISA: 1:2000-1:10,000Western Blot: 1:200-1:1000Immunohistochemistry (Paraffin): 5ug/mlImmunofluorescence: 1:2000-1:10,000Optimal dilutions to be determined by the researcher.
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for 12 months.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size：50ug
Host：rabbit
Source Antibody：human
Grade：Affinity Purified
Purity：Purified by immunoaffinity chromatography.
Form：Supplied as a liquid in PBS, pH 7.2, 0.01% sodium azide.
Specificity：Recognizes human Transforming Growth Factor, beta 1 (TGFb1). Species Crossreactivity: mammal and rabbit
Isotype：IgG
Calc Applications Abbrev：E IF IHC WB
Calc Crossreactivity：Hu Ma Rb
Immunogen：Synthetic peptide corresponding to aa286-293 of full-length (including signal peptide) precursor TGFb protein. This sequence also corresponds with aa8-15 (of 112) of the mature growth factor.
