Serotonin (5-hydroxytryptamine, 5-HT) receptor 5-HT7, belongs to the G-protein coupled receptor superfamily.
Serotonin is a neurotransmitter and vasoactive amine which is thought to play a role in various cognitive and behavioral functions including pain, appetite, mood and sleep.
Signalling through 5-HT7 has several effects, including regulation of the circadian rhythm and mediation of smooth-muscle relaxation in the vasculature and gastrointestinal tract.
Signalling though 5-HT7 has also been shown to contribute to early T-cell activation.
5-HT7 has been implicated in depression, autism, and other neuropsychiatric disorders.
Applications:Suitable for use in Immunohistochemistry.
Other applications not tested.
Recommended Dilution:Immunohistochemistry (paraffin): 10ug/ml, requires antigen retrieval using heat treatment prior to staining of paraffin sections.
Sodium citrate, pH 6.0 is recommended
Optimal dilutions to be determined by the researcher.
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for 12 months.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size：50ug
Host：rabbit
Source Antibody：human
Grade：Affinity Purified
Purity：Purified by immunoaffinity chromatography.
Form：Supplied as a liquid in PBS, 0.09% sodium azide.
Specificity：Recognizes Human 5-HT7 Receptor (HTR7).
Isotype：IgG
Calc Applications Abbrev：IHC
Calc Crossreactivity：Hu
Immunogen：Synthetic peptide corresponding to the C-terminal region of human 5-HT7 receptor, conjugated to KLH.
