The activity-dependent neuroprotective protein (hADNP) gene is frequently amplified in many neoplasias, including breast, bladder, ovarian, pancreatic, and colon cancers.
hADNP mRNA is abundantly expressed in distinct normal tissues, and high expression levels were encountered in malignant cells.
hADNP is implicated in maintaining cell survival, perhaps through modulation of p53.
Applications:Suitable for use in Western Blot.
Other applications not tested.
Recommended Dilution:Western Blot: 1:500-1:1000Optimal dilutions to be determined by the researcher.
Storage and Stability:May be stored at 4°C for short-term only.
For long-term storage and to avoid repeated freezing and thawing, aliquot and store at -20°C.
Aliquots are stable for at least 12 months at -20°C.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Further dilutions can be made in assay buffer.
仕様
Size：100ul
Host：rabbit
Source Antibody：human
Grade：Affinity Purified
Purity：Purified by immunoaffinity chromatography.
Form：Supplied as a liquid in PBS, 0.02% sodium azide.
Specificity：Reacts with residues 907-923 [RQMQRTITRQMpS919FDLTK] of the human 220kD Kidins220 protein (serine 919 has been phosphorylated pS919). Species Crossreactivity: Mouse.
Isotype：IgG
Calc Applications Abbrev：WB
Calc Crossreactivity：Hu Mo
Immunogen：Synthetic peptide corresponding to residues 907-923 [RQMQRTITRQMpS919FDLTK] of human Kidins220 protein (serine 919 has been phosphorylated pS919).
