OXPAT is a novel PAT-1 protein that is expressed in highly oxidative tissues.
Lipid droplet proteins of the PAT family regulate cellular neutral lipid stores.
OXPAT is induced by physiological (fasting), pathophysiological (insulin deficiency), pharmacological (peroxisome proliferator-activated receptor [PPAR] agonists), and genetic (muscle-specific PPAR alpha overexpression) disturbances that increase fatty acid utilization.
It is suggested that OXPAT is a marker for PPAR activation and fatty acid oxidation.
As well, it may contribute to adaptive responses to the fatty acid responsibility that accompanies fasting, insulin deficiency, and overnutrition, responses that are defective in obesity and type 2 diabetes.
Applications:Suitable for use in ELISA, Western Blot.
Other applications not tested.
Recommended Dilution:Western Blot: 0.5-2ug/ml Optimal dilutions to be determined by the researcher.
Storage and Stability:For long-term storage, aliquot and store at -20°C.
Aliquots are stable for at least 12 months at -20°C.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Further dilutions can be made in assay buffer.
仕様
Size：100ul
Host：rabbit
Source Antibody：human
Grade：Affinity Purified
Purity：Purified by immunoaffinity chromatography.
Form：Supplied as a liquid in 1mg/ml PBS, 30% glycerol, 0.09% sodium azide.
Specificity：Homology: 100% homology with human and dog proteins; 94% homology with cow protein; 84% homology with mouse and rat proteins.
Isotype：IgG
Calc Applications Abbrev：E WB
Calc Crossreactivity：Hu Mo
Immunogen：Synthetic peptide made to a region of the human OXPAT protein, within residues 300-400. [Uniprot# Q00G26] .
