MLDP is a novel PAT-1 protein that is expressed in highly oxidative tissues.
Lipid droplet proteins of the PAT family regulate cellular neutral lipid stores.
MLDP is induced by physiological (fasting), pathophysiological (insulin deficiency), pharmacological (peroxisome proliferator-activated receptor [PPAR] agonists), and genetic (muscle-specific PPAR alpha overexpression) disturbances that increase fatty acid utilization.
It is suggested that MLDP is a marker for PPAR activation and fatty acid oxidation.
As well, it may contribute to adaptive responses to the fatty acid responsibility that accompanies fasting, insulin deficiency, and overnutrition, responses that are defective in obesity and type 2 diabetes.
Applications:Suitable for use in ELISA and Western Blot.
Other applications not tested.
Recommended Dilutions:Western Blot: 0.5-2ug/ml.
Detects a band at ~50kD
Optimal dilutions to be determined by the researcher.
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for 12 months.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size：100ul
Host：rabbit
Source Antibody：mouse
Grade：Affinity Purified
Purity：Purified by immunoaffinity chromatography.
Form：Supplied as a liquid in PBS, 0.09% sodium azide, 30% glycerol.
Specificity：Recognizes mouse MLDP. Species crossreactivity: human. Species Sequence Homology: rat; 89%, bovine; 75%.
Isotype：IgG
Calc Applications Abbrev：E WB
Calc Crossreactivity：Hu Mo
Immunogen：Synthetic peptide corresponding to the C-terminal region, 400-463, of the mouse MLDP.
