LILRC2 (leukocyte immunoglobulin-like receptor C2) is a 35kD member of a family of inhibitory and stimulatory receptors (LILRs) that are expressed on hematopoietic cells.
Mature rat LILRC2 is a type I transmembrane (TM) protein that is 241 amino acids (aa) in length.
It contains a 207 aa extracellular domain (ECD), a 19 aa TM segment, and a short cytoplasmic tail.
The ECD contains two Ig-like domains while the TM segment possesses an Arg residue.
This suggests that LILRC2 is an activating receptor that may interact with FcεRIγ and/or CD3ζ.
Cells expressing LILRC2 include neutrophils, B cells, and CD4+ and CD8+ T cells.
No human or mouse LILRC2 is known.
Applications:Suitable for use in Western blot.
Other applications have not been tested.
Recommended Dilutions:Western Blot: 0.1-0.2ug/ml
Storage and Stability:Lyophilized powder may be stored at 4°C for short-term only.
Reconstitute to nominal volume by adding sterile 40-50% glycerol, aliquot and store at -20°C.
Reconstituted product is stable for 12 months at -20°C.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Further dilutions can be made in assay buffer.
仕様
Size:50ug
Host:sheep
Source Antibody:rat
Grade:Affinity Purified
Purity:Purified by immunoaffinity chromatography.
Form:Supplied as a lyophilized powder from PBS with BSA. Labeled with biotin. Reconstitute with 1ml sterile 0.1% BSA in TBS to a concentration of 0.05mg/ml.
Specificity:Recognizes rat LILRC2 extracellular domain. Cross-reactivity: rrLILRC1 25%.
Isotype:IgG
Calc Applications Abbrev:WB
Calc Crossreactivity:Rt
Immunogen:NS0-derived recombinant rat rrLILRC2 extracellular domain.