84-1091-37 REDD1 (Regulated in Development and DNA damage responses) 100ul R1300-70
特徴
- REDD1 (Regulated in Development and DNA damage responses) expression is induced by hypoxia, cell stress, apoptosis and DNA damage.
- REDD1 is a transcriptional target of p53 and p63 following DNA damage, and links p63 to Ros (1).
- REDD1 functions as a negative regulator of mTOR in response to hypoxia in a tuberin-dependent manner (2).
- Depending on cell context, REDD1 can either be protecting or detrimental for cells under oxidative or ischemic stresses (3).
- Applications:Suitable for use in Western Blot.
- Other applications not tested.
- Recommended Dilution:Western Blot: 1:1000Optimal dilutions to be determined by the researcher.
- Storage and Stability:May be stored at 4°C for short-term only.
- For long-term storage, aliquot and store at -20°C.
- Aliquots are stable for 12 months at -20°C.
- For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
- Further dilutions can be made in assay buffer.
仕様
- Size：100ul
- Host：rabbit
- Source Antibody：human
- Grade：Affinity Purified
- Purity：Purified by peptide affinity chromatography.
- Form：Supplied as a liquid in 10mM sodium HEPES, pH 7.5, 150mM sodium chloride, 0.1mg/ml BSA, 50% glycerol.
- Specificity：Recognizes transfected levels of human REDD1 protein.
- Isotype：IgG
- Calc Applications Abbrev：WB
- Calc Crossreactivity：Hu
- Immunogen：Synthetic peptide surrounding Asn60 of human REDD1.
- Shelf Life：1year
- Swiss Prot Number：Q9NX09
- EU Commodity Code：30021010
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