TREML2, also known as TLT2 (TREM-like transcript 2), is a transmembrane protein in the TREM family of immunoregulatory molecules.
TREML2 contains one Ig-like V-type domain and a Ser-Thr rich region.
Unlike other TREM proteins, TREML2 lacks cytoplasmic ITIM and ITAM motifs and a DAP12-interacting transmembrane segment.
TREML2 is expressed throughout the B cell lineage, and it is upregulated in neutrophils and macrophages in response to inflammatory stimuli.
The extracellular regions of human and mouse TREML2 share 54% amino acid sequence identity.
Applications:Suitable for use in ELISA and Western Blot.
Other applications have not been tested.
Recommended Dilution:Western Blot: 0.1ug/ml validated using recombinant human TREML2/TLT-2 Fc chimera cell lineOptimal dilutions should be determined researcher.
Storage and Stability:Lyophilized powder may be stored at -20°C.
Stable for 12 months after receipt at -20°C.
Reconstitute with sterile PBS.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Further dilutions can be made in assay buffer.
仕様
Size：100ug
Host：goat
Source Antibody：human
Grade：Affinity Purified
Purity：Purified by immunoaffinity chromatography.
Form：Supplied as a lyophilized powder from PBS, pH 7.4, 5% trehalose. Reconstitute with 500ul sterile PBS.
Specificity：Recognizes human TREML2. Less than 1% crossreactivity with recombinant human TREML1.
Isotype：IgG
Calc Applications Abbrev：E WB
Calc Crossreactivity：Hu
Immunogen：Recombinant protein corresponding to Gly19-Ser268 from NS0-derived rhTREML2 (Q5T2D2)
