Hepatocyte growth factor receptor (HGF R), also known as c-MET, is a receptor tyrosine kinase that consists of an extracellular α chain and a longer β chain.
The β chain contains the transmembrane helix and the cytoplasmic portion.
Ligand-stimulated phosphorylation of Y1349 in HGF R’s β chain allows the binding of Gab1.
Applications:Western Blot: 0.5ug/ml is recommended.
Optimal dilutions should be determined by each laboratory for each application.
Storage and Stability:Lyophilized powder may be stored at 4°C for short-term only.
Reconstitute to nominal volume by adding sterile PBS, 0.02% sodium azide, 40-50% glycerol and store at -20°C.
Reconstituted product is stable for 12 months at -20°C.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Further dilutions can be made in assay buffer.
仕様
Size：50ug
Host：rabbit
Source Antibody：human
Grade：Affinity Purified
Purity：Purified by immunoaffinity chromatography.
Form：Supplied as a lyophilized powder from a 0.2um filtered solution in PBS, 5% trehalose.
Specificity：Detects endogenous human HGF R/c-MET phosphorylated at Y1349.
Isotype：IgG
Calc Applications Abbrev：WB
Calc Crossreactivity：Hu
Immunogen：Phosphopeptide containing Y1349 site of human HGF R
