84-1088-88　Glutathione Peroxidase 3 (GPX3, GSHPx-3, GPx-3, GSHPx-P, GPx-P, GPXP) 100ug　G8127-13

特徴

• Glutathione Peroxidase 3 (GPX3), also known as Plasma Glutathione Peroxidase, is a 226aa member of the glutathione peroxidase antioxidant enzyme family.
• The Glutathione Peroxidase family protects cell surfaces, extracellular fluid components, and enzymes from oxidative stress by catalysing the reduction of hydrogen peroxide, lipid peroxides, and organic hydroperoxide using reduced glutathione.
• GPX3 is secreted into plasma and like GPX1, is an ~100kD homotetramer consisting of four identical 23kD subunits, each containing a selenocysteine residue at the active site.
• GPX3 exhibits highest levels of mRNA expression in liver (human only), kidney, heart and lung tissues.
• Mouse GPX3 shares 89% and 99% amino acid identity with human and rat GPX3, respectively.
• Applications:Suitable for use in Western Blot, Immunohistochemistry and Immunocytochemistry.
• Other applications not tested.
• Recommended Dilution:Western Blot: 1ug/mlImmunohistochemistry: 2-15ug/mlImmunocytochemistry: 2-15ug/mlOptimal dilutions to be determined by the researcher.
• Recommended Secondary Antibodies:I1904-28K: IgG, H&L (HRP) Pab Rb xGtI1904-28Q: IgG, H&L, X-Adsorbed (HRP) Pab Rb xGtI1904-28V: IgG, (HRP) Pab Rb xGtI1904-29A: IgG, (HRP) Pab Rb xGt
• Storage and Stability:Lyophilized powder may be stored at -20°C.
• Stable for 12 months at -20°C.
• Reconstitute with sterile PBS, 0.02% sodium azide.
• Aliquot to avoid repeated freezing and thawing.
• Store at -20°C.
• Reconstituted product is stable for 12 months at -20°C.
• For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
• Further dilutions can be made in assay buffer.