Artemin is a novel member of the GDNF family and demonstrated that it is the ligand for the former orphan receptor GFRalpha3-RET.
Artemin is a survival factor for sensory and sympathetic neurons in culture, and its expression pattern suggests that it also influences these neurons in vivo.
Artemin can also activate the GFRalpha1-RET complex and supports the survival of dopaminergic midbrain neurons in culture
Applications:Suitable for use in ELISA and Western Blot.
Used in conjunction with compatible secondary reagents, allows the detection of at least 2000-4000pg/well of recombinant human ArteminWestern Blot: 0.1-0.2ug/ml.
Detection limit for recombinant human Artemin is 1.5-3ng/lane, under either reducing or non-reducing conditions
Optimal dilutions to be determined by the researcher.
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for 12 months after receipt.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size:100ug
Host:rabbit
Source Antibody:human
Grade:Affinity Purified
Purity:Purified by immunoaffinity chromatography.
Form:Supplied as a liquid in PBS, pH 7.2.
Specificity:Recognizes human Artemin.
Isotype:IgG
Calc Applications Abbrev:E WB
Calc Crossreactivity:Hu
Immunogen:Recombinant protein corresponding to human Artemin, expressed in E.coli.