84-1087-34 Proteasome 19S, Subunit S5A (PSMD4) 100ul P9078-25B
特徴
- S5a(PSMD4) is a subunit of the 19S regulatory proteasome complex functioning in ubiquitinylated-protein targeting and degradation.
- S5a contains two polyubiquitin binding motifs (UIM) which bind multiubiquitin chains by hydrophobic interaction.
- In addition to ubiquitin, the UIM of S5a shows high affinity to a ubiquitin-like domain present in many proteins.
- S5a binds to these types of protein directly and mediates their targeting to the proteasome for degradation.
- Applications:Suitable for use in Western Blot.
- Other applications not tested.
- Recommended Dilution:Western Blot: 1:1000Optimal dilutions to be determined by the researcher.
- Storage and Stability:May be stored at 4°C for short-term only.
- Aliquot to avoid repeated freezing and thawing.
- Store at -20°C.
- Aliquots are stable for 12 months after receipt.
- For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
- Size：100ul
- Host：rabbit
- Source Antibody：human
- Grade：Affinity Purified
- Purity：Purified by Protein A and peptide affinity chromatography.
- Form：Supplied as a liquid in 10mM sodium HEPES, pH 7.5, 150mM sodium chloride, 0.1mg/ml BSA, 50% glycerol.
- Specificity：Detects endogenous levels of total human S5a/PSMD4 protein, 49kD. Species Crossreactivity: Monkey, mouse and rat.
- Isotype：IgG
- Calc Applications Abbrev：WB
- Calc Crossreactivity：Hu Mk Mo Rt
- Immunogen：Synthetic peptide corresponding to residues surrounding Gly344 of human S5a/PSMD4.
- Shelf Life：1year
- Swiss Prot Number：P55036
- EU Commodity Code：30021010
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