Parathyroid Hormone-like related Protein (PTHrP) is a member of the Parathyroid hormone family that is expressed in the mammary gland.
It is known as a potent inhibitor of chondrocyte maturation.
PTHrP is expressed by periarticular perichondrial cells and exerts its biological activity on PP-R expressing cells.
During endochondral bone development PTHrP plays a major role in suppressing the onset of hypertrophic differentiation.
It is also responsible for most cases of humoral hypercalcemia of malignancy.
Applications:Suitable for use in Western Blot, Immunohistochemistry, and for passive immunization.
Other applications not tested.
Recommended Dilutions:Optimal dilutions to be determined by the researcher.
Storage and Stability:Lyophilized powder may be stored at -20°C.
Stable for 12 months after receipt at -20°C.
Reconstitute with sterile PBS.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Reconstituted product is stable for 12 months at -20°C.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Further dilutions can be made in assay buffer.
仕様
Size：100ul
Host：rabbit
Grade：Serum
Purity：Serum
Form：Supplied as a lyophilized powder. Reconstitute with 100ul sterile PBS.
Specificity：Recognizes PTHrp (1-35). Reactivity towards human and bovine PTH (1-34) is >1% and reactivity towards human PTH(1-84) is >0.5%. Does not react with Atrial Natriuretic Polypeptide (Human), ACTH (Human, 1-39), Calcitonin (Human), Epidermal growth factor (Human), Somatostatin 28, Transforming Growth Factor-alpha (Human) and VIP.
Isotype：IgG
Calc Applications Abbrev：IHC WB
Immunogen：Synthetic PTH related peptide (1-35) which is also known as Hypercalcemia Maligancy Peptide (1-35), covalently attached onto a carrier protein.
