Insulin Like Growth Factor-I (IGF-I) is a polypeptide growth factor which stimulates the proliferation of a wide range of cell types including muscle, bone, and cartilage tissue.
Recombinant Human IGF-I is a single, nonglycosylated, 7.6kD protein containing 70 amino acid residues.
Insulin-like growth factor 1 (IGF-I) is involved in regulation of neuronal growth and development in central and peripheral nervous system.
It is known to protect neurons against cell death induced by amyloidogenic derivatives, glucose or serum deprivation through pathways involving AKT kinase and transcription factor FKHRL1 phosphorylation.
Activation of the insulin-like growth factor system has emerged as a key factor for tumor progression and resistance to apoptosis in many cancers like breast and thyroid cancers.
Applications:Suitable for use in RIA, ELISA and Immunoprecipitation.
Other applications not tested.
Recommended Dilutions:Optimal dilutions to be determined by the researcher.
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for 12 months after receipt.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size：50ul
Host：rabbit
Source Antibody：human
Grade：Highly Purified
Purity：Purified by precipitation, dialysis and column chromatography.
Form：Supplied as a liquid in PBS.
Specificity：Recognizes Insulin-like growth factor 1 (human). Crossreactivity: rat IGF-1; 80%, human and rat IGF-2; <0.1%. Does not react with human Insulin, human Atrial natriuretic peptide, ACTH, human Calcitonin, EGF, Somatostatin, TGF alpha or Vasoactive Intestinal Peptide.
Isotype：IgG
Calc Applications Abbrev：E IP RIA
Calc Crossreactivity：Hu
Immunogen：Synthetic human insulin-like growth factor 1 covalently attached onto a carrier protein.
