84-1083-23　Neuropeptide Y3 Receptor (NPY 3R) 100ug　N2176-64

特徴

• Neuropeptide Y (NPY), a neuropeptide colocalized and abundantly released with the neurotransmitter norepinephrine in nervous system, synthesized by postnatal olfactory epithelium of sustentacular cells.
• It promotes the proliferation of postnatal neuronal precursor cells and exhibits a diverse range of important physiologic activities, including effects on psychomotor activity, food intake, regulation of central endocrine secretion, and potent vasoactive effects on the cardiovascular system.
• NPY a 97aa peptide in mouse, human (chr 7p15.1) and 98aa in rat has a mol.
• wt of 11kD.
• NPY shows sequence homology to Peptide YY (PYY) and over 50% homology in amino acid and nucleotide sequence to Pancreatic Polypeptide (PNP or PPY), all of these homologous peptides has a 36aa mature peptide characterized by a hairpin loop.
• NPY3R/ CXCR4/ LSTR/ Fusin/ Chemokine, a 359aa protein in mouse, rat and 352 in human (chr 2q21), it shows 21% identity to NPY1R, they may help in activation of inflammatory cells.
• Applications:Suitable for use in ELISA.
• Western Blot, though not tested, may potentially be used as an application.
• Other applications not tested.
• Recommended Dilutions:ELISA: 0.5-1ug/ml; Control peptide can be used to coat ELISA plates at 1ug/ml.
• Western Blot: 1-10ug/ml (ECL)Optimal dilutions to be determined by the researcher.
• Recommended Control Peptide:N2176-64B: Neuropeptide Y3 Receptor, Human, Control Peptide (NPY 3R)
• Storage and Stability:May be stored at 4°C for short-term only.
• Aliquot to avoid repeated freezing and thawing.
• Store at -20°C.
• Aliquots are stable for 12 months after receipt.
• For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.