Adiponectin receptor 2/ADIPOR2, a 311-aa protein (mouse) with a Mol.wt of 35.4kD and human ADIPOR2 has 299aa which shares 95.2% homology with that of mouse.
The ADIPOR2 serves as receptor for globular and full-length adiponectin and mediate increased AMPK and PPAR-alpha ligand activities, as well as fatty acid oxidation and glucose uptake by adiponectin.
ADIPOR2 is most abundantly expressed in Liver.
Applicatons:Suitable for use in Western Blot and ELISA.
Other applications not tested.
Recommended Dilution:Western Blot:1-10ug/ml for affinity pure antibody using ECL technique
ELISA: 0.5-1ug/ml, Control peptide can be used to coat ELISA plates at 1ug/ml
Optimal dilution determined by the researcher.
Storage and Stability:May be stored at 4°C for short-term only.
For long-term storage, store at -20°C.
Aliquots are stable for at least 12 months at -20°C.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Further dilutions can be made in assay buffer.
仕様
Size:100ul
Host:rabbit
Source Antibody:mouse
Grade:Affinity Purified
Purity:Purified by immunoaffinity chromatography.
Form:Supplied as a lyophilized powder from PBS, 0.05% sodium azide.
Specificity:Adiponectin receptor 2/ADIPOR2, a 311-aa protein (mouse) with a Mol.wt of 35.4kD and human ADIPOR2 has 299aa which shares 95.2% homology with that of mouse. The ADIPOR2 serves as receptor for globular and full-length adiponectin and mediate increased AMPK and PPAR-alpha ligand activities, as well as fatty acid oxidation and glucose uptake by adiponectin. ADIPOR2 is most abundantly expressed in Liver. Mouse shows 94% and 82% sequence homology with rat and human ADIPOR1. No significant homology exists with ADIPOR2.
Isotype:IgG
Calc Applications Abbrev:E WB
Calc Crossreactivity:Mo
Immunogen:18-aa peptide from Mouse ADIPOR1, conjugated to KLH~N-terminus, Cytoplasmic domain