84-1081-34 Delta 4 (Delta-like protein 4, DLL4, Drosophila Delta homolog 4, notch ligand DLL4 precursor) 100ug D2728
特徴
- Delta 4 (Delta 4 Precursor, Delta Ligand 4 Precursor, Delta-like Protein 4, DLL4, Drosophila Delta Homolog 4, Notch Ligand DLL4 Precursor) is a homolog of the Drosophila delta protein.
- The delta gene family encodes Notch ligands that are characterized by a DSL domain, EGF repeats, and atransmembrane domain.
- DELTA-4 plays a role in the Notch signaling pathway and activates Notch-1 and Notch-4.
- DELTA-4 is a membrane protein that is expressed in the vascular endothelium.
- Applications:Suitable for use in ELISA, Immunohistochemistry and Western Blot.
- Other applications not tested.
- Recommended Dilution:ELISA: 1:5000-1:25,000Immunohistochemistry (FFPE): 10-20ug/ml; Detects Delta 4 in a variety of tissues including colon, liver, skeletal muscle, ovary, pancreas, prostate, testes, thymus, tonsil and uterus.
- In contrast to reports, no staining was observed in vascular tissue
- Western Blot: 1:500-1:2500.
- Recognizes a band ~74kD
- Optimal dilutions to be determined by the researcher.
- Storage and Stability:May be stored at 4°C for short-term only.
- Aliquot to avoid repeated freezing and thawing.
- Store at -20°C.
- Aliquots are stable for at least 12 months.
- For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
- Size:100ug
- Host:rabbit
- Source Antibody:human
- Grade:Affinity Purified
- Purity:Purified by immunoaffinity chromatography.
- Form:Supplied as a liquid in PBS, pH 7.2, 0.01% sodium azide. No stabilizing proteins added.
- Specificity:Recognizes human Delta 4. Species Sequence Homology: mouse, rat and chimpanzee (91%).
- Isotype:IgG
- Calc Applications Abbrev:E IHC WB
- Calc Crossreactivity:Hu
- Immunogen:Synthetic peptide corresponding to an internal region of human Delta 4.
- Shelf Life:1year
- EU Commodity Code:30021010
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