A novel rat gene, Rattin, encodes a peptide homologous to Humanin, a secreted peptide that specifically protects against neuronal cell death induced by beta-amyloid peptide or by mutations causing early-onset familial Alzheimer's disease.
Rattin is the prototype of a novel class of peptides, phylogenetically related to Humanin, endowed with protective activity not only against beta-amyloid peptide but also toward excitotoxic neuronal death.
The rat gene, Rattin, encodes a peptide of 38 residues (15 residues longer than Humanin) showing 73% identity in the conserved region to Humanin.
Applications:Suitable for use in Western Blot performed from 100ng of synthetic Rattin peptide and from 50mg of total lysates of 293T cells transfected with plasmids encoding GFP-Rattin.
Other applications not tested.
Recommended Dilution:Optimal dilutions to be determined by the researcher.
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for 12 months after receipt.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size：100ul
Host：rabbit
Source Antibody：rat
Grade：Affinity Purified
Purity：Purified by immunoaffinity chromatography.
Form：Supplied as a liquid.
Specificity：Recognizes rat Rattin.
Isotype：IgG
Calc Applications Abbrev：WB
Calc Crossreactivity：Rt
Immunogen：VKRLESPNKTRRPYGA (aa20-35 of the rat Rattin peptide)
