84-1081-03　Opioid Receptor 1C, mu (MOR1C) 50ul　O7030-36C

特徴

• Three types of opioid receptors have been cloned -- mu, delta, and kappa.
• Opioid receptors are seven transmembrane G-protein coupled receptors.
• They share a high degree of homology and are most divergent at the N- and C-termini.
• Activation of mu opioid receptors leads to a decrease in neuronal excitability.
• Several C-terminal splice variants have been identified for the Mu Opioid Receptor (MOR1) including MOR1C.
• These splice variants appear to differ in their pharmacological selectivity as well as their membrane trafficking.
• Applications:Suitable for use in Immunohistochemistry.
• Other applications not tested.
• Recommended Dilution:Immunohistochemistry: 1:5000-1:10000.
• Use perfusion fixed tissues.
• Perfusion: Calcium free Tyrodes solution, paraformaldehyde-picric acid fixative, and 10% sucrose in PBS as a cryo-protectant.
• Optimal dilutions to be determined by the researcher.
• Storage and Stability:May be stored at 4°C for short-term only.
• Aliquot to avoid repeated freezing and thawing.
• Store at -20°C.
• Aliquots are stable for 12 months after receipt.
• For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.