84-1079-85　［取扱停止］Musashi-1 RNA Binding Protein (Mi, Msi-1) 100ug　M9515-01G

特徴

• Musashi1, a neural RNA-binding protein, plays an important role in regulating cell differentiation in precursor cells.
• Musashi-1 (Msi-1) has been shown to increase the accumulation of tau isoforms in intracellular inclusions in dementia and Parkinson's.
• The presence of Msi-1 in a significant percentage of neurons containing cytoplasmic inclusions in 2 other neurodegenerative diseases Alzheimer's disease and Pick disease suggests that it may play a role in the pathogenesis of these neurodegenerative disorders.
• Musashi1 has also been detected in human tumor tissues such as gliomas and melanomas, suggesting its involvement in cancer development.
• Msi-1 also appears to play a vital role in the development of several types of carcinoma such as human hepatoma and may be a useful molecular marker for tumor detection.
• Applications:Suitable for use in Western Blotting, Immunohistochemistry, Immunocytochemistry.
• Other applications not tested.
• Recommended Dilution:Western Blotting:1:500Immunohistochemistry:1:100Immunocytochemistry:1:100
• Optimal dilutions to be determined by the researcher.
• Storage and Stability:May be stored at 4°C for short-term only.
• For long-term storage and to avoid repeated freezing and thawing, add glycerol (40-50%)aliquot and store at -20°C.
• Aliquots are stable for at least 12 months at -20°C.
• For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
• Further dilutions can be made in assay buffer.