84-1079-31 Optineurin (FIP-2, NEMO-Related Protein, NRP) 500ul O7037
特徴
- Optineurin (OPTN) has recently been linked to glaucoma, a major cause of blindness worldwide.
- Mutations in OPTN such as Glu50->Lys (E50K) have been reported in patients, particularly those with normal pressure glaucoma.
- Applications:Suitable for use in Immunohistochemistry and Western Blot.
- Other aapplications not tested.
- Recommended Dilutions: Immunohistochemistry: 10ug/ml (1hour incubation at RT).
- Overnight incubations at 4ºC with lesser IgG concentrations present good results
- Western blot: 3ug/mlOptimal dilutions to be determined by the researcher.
- Storage and Stability:May be stored at 4°C for short-term only.
- Aliquot to avoid repeated freezing and thawing.
- Store at -20°C.
- Aliquots are stable for 12 months.
- For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
- Size:500ul
- Host:rabbit
- Source Antibody:human
- Grade:Affinity Purified
- Purity:Purified by immunoaffinity chromatography.
- Form:Supplied as a liquid in TBS, pH 7.4, 0.02% sodium azide, 0.5mg/ml BSA, 50% glycerol.
- Specificity:Recognizes human optineurin. Does not cross-react with mouse, rat and porcine optineurin.
- Isotype:IgG
- Calc Applications Abbrev:IHC WB
- Calc Crossreactivity:Hu
- Immunogen:Synthetic peptide corresponding to aa115-130 (KGKSERSSEDPTDDSR) of human optineurin (FIP-2 (14.7K interacting protein-2); NRP (nemo-related protein)).
- Shelf Life:1year
- EU Commodity Code:30021010
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