It is receptor for the MCP-1, MCP-3 and MCP-4 chemokines.
It transduces a signal by increasing the intracellular calcium ions level.
It is an alternative coreceptor with CD4 for HIV-1 infection.
Applications:Suitable for use in Immunocytochemistry, Immunohistochemistry and Western Blot.
Other applications not tested.
Recommended Dilutions:Immunocytochemistry: 1:400Immunohistochemistry (Paraffin sections): 1:200Western Blot: 1:1000Optimal dilutions to be determined by the researcher.
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for 12 months after receipt.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size:200ug
Host:goat
Source Antibody:human
Grade:Affinity Purified
Purity:Purified by immunoaffinity chromatography.
Form:Supplied as a liquid in PBS, 1mg/ml BSA, 0.09% sodium azide.
Specificity:Recognizes human CCR2.
Isotype:IgG
Calc Applications Abbrev:IC IHC WB
Calc Crossreactivity:Hu
Immunogen:Synthetic peptide corresponding to aa17-39 (GEEVTTFFDYDYGAPCHKFDVKQ) of the N-terminal extracellular domain of human CCR2 (C-C chemokine receptor 2).