Receptors for the C-C chemokine family include CCR 1, CCR 2A, CCR 3, CCR 4, CCR 5 and the Duffy blood group antigen.
The C-C receptors are important in the function of T cell chemotaxis and migration of phagocytic cells to sites of inflammation.
The CCR8 receptor in particular mediates CC chemokine I 309 induced monocyte chemoattraction, HIV 1 envelope fusion and virus infection.
Applications:Suitable for use in Western Blot, ELISA, Immunohistochemistry and Immunocytochemistry.
Other applications not tested.
Recommended Dilution:Immunocytochemistry: 1:500Immunohistochemistry (Paraffin): 1:400 Western Blot: 1:1000Optimal dilutions to be determined by the researcher.
Positive Control: Mouse spleen cells.
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for 12 months after receipt.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size：200ug
Host：goat
Source Antibody：mouse
Grade：Affinity Purified
Purity：Purified by immunoaffinity chromatography.
Form：Supplied as a liquid in PBS, pH 7.2, 1mg/ml BSA, 0.09% sodium azide.
Specificity：Recognizes mouse CCR8.
Isotype：IgG
Calc Applications Abbrev：E IC IHC WB
Calc Crossreactivity：Mo
Immunogen：Synthetic peptide corresponding to aa7-33, PNVTMTDYYPDFFTAPCDAEFLLRGSM of mouse CCR8 (C-C chemokine receptor 8).
