Interleukin 10 (IL-10) is an anti-inflammatory cytokine mainly produced by macrophages and Th2 cells.
IL-10 functions by inhibiting pro-inflammatory cytokines made by macrophages and regulatory T cells including, IFN-gamma, TNF-alpha, IL-2, and IL-3, IL-4, and GM-CSF.
IL-10 is also known to suppress antigen presentation on antigen presenting cells.
While human IL-10 can act on murine cells, murine IL-10 cannot act on human cells.
Applications:Suitable for use in ELISA, Western Blot and Immunohistochemistry.
Other applications not tested.
Recommended Dilutions:Optimal dilutions to be determined by the researcher.
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for 12 months after receipt.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size:500ug
Host:rabbit
Source Antibody:rat
Grade:Affinity Purified
Purity:Purified by Protein A/G affinity chromatography.
Form:Supplied as a liquid in PBS, pH 7.2. Carrier and preservative free.
Specificity:Recognizes natural and recombinant rat IL-10.
Isotype:IgG
Calc Applications Abbrev:E IHC WB
Calc Crossreactivity:Rt
Immunogen:Purified recombinant rat IL-10 with full biological activity when compared to standard.