Interleukin 1 beta (IL-1b) and Interleukin 1 alpha (IL-1a) have very similar biological activities on many different cell types although they are derived from different genes and share only ~20% aa sequence homology.
IL-1b is synthesized as pro-IL-1b in cells and is cleaved to produce active IL-1b by Interleukin-1b converting enzyme (ICE), a cytoplasmic cysteine protease which is also known as caspase-1.
Applications:Suitable for use in Western Blot.
The antibody is not neutralizing when tested in a proliferation assay.
Other applications not tested.
Recommended Dilution:Western Blot: 0.5-2ug/mlOptimal dilutions to be determined by the researcher.
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for 12 months after receipt.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size:500ug
Host:rabbit
Source Antibody:porcine
Grade:Affinity Purified
Purity:Purified by Protein G affinity chromatography.
Form:Supplied as a liquid in PBS, pH 7.2. No preservative added.
Specificity:Recognizes porcine IL-1b. Does not react with porcine IL-1a.