Ig α-1 chain C region is a protein encoded by the IGHA1 gene in humans.
IgA deficiency (IgAD) is the most common immunodeficiency and it has 2 subclasses, they are IgA1 and IgA2.
Its heavy chains are encoded by the α1 and α2 genes.
Galactose-deficient IgA1 (GdIgA1) has an important role in the pathogenesis of IgA nephropathy (IgAN).
It can act as a useful non-invasive IgAN biomarker.
Immunoglobulin A nephropathy (IgAN) is associated with genetic as well as environmental factors and undergalactosylation of IgA1 in the serum may contributor to pathogenesis of IgAN.
Applications:Suitable for use in Western Blot.
Other applications not tested.
Recommended Dilution:Western Blot: 1:500Optimal dilutions to be determined by the researcher.
Recommended Secondary Antibodies:I1906-10IgY, Chicken-HRP Rb x Ch I1906-12IgY, Chicken-FITC Rb x Ch I1906-14IgY, Chicken-AP Rb x Ch
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for 12 months after receipt.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size：50ug
Host：chicken
Source Antibody：human
Grade：Affinity Purified
Purity：Purified by immunoaffinity chromatography.
Form：Supplied as a liquid in PBS, pH 7.2, 0.02% sodium azide.
