This intronless gene is a member of the frizzled gene family.
Members of this family encode seven-transmembrane domain proteins that are receptors for the wingless type MMTV integration site family of signaling proteins.
This gene encodes a protein that is coupled to the beta-catenin canonical signaling pathway.
Competition between the wingless-type MMTV integration site family, member 3A and wingless-type MMTV integration site family, member 5A gene products for binding of this protein is thought to regulate the beta-catenin-dependent and -independent pathways.
Applications:Suitable for use in Immunoprecipitation and Western Blot.
Other applications have not been tested.
Recommended Dilution:Immunoprecipitation: 7ug/reactionWestern Blot: 1-3ug/mlOptimal dilutions to be determined by the researcher.
Positive Controls:Immunoprecipitation: HepG2 cells Western Blot: Human CaCO2, PC-3, SKOV3, SW480, HepG2 and HEK293 cell lysates
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for 12 months after receipt.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size：100ug
Host：rabbit
Source Antibody：human
Grade：Affinity Purified
Purity：Purified by immunoaffinity chromatography.
Form：Supplied as a liquid in PBS, pH 7.4, 0.09% sodium azide.
Specificity：Recognizes human FZD2. On Western blots, it identifies a band at ~85kD.
Isotype：IgG
Calc Applications Abbrev：IP WB
Calc Crossreactivity：Hu
Immunogen：Synthetic peptide derived from the N-terminal region of human Frizzled-2 (FZD2). Species Sequence Homology: mouse
