Neurogenins are a family of bHLH transcription factors involved in specifying neuronal differentiation.
They are related to Drosophila atonal.
The neurogenins (ngns) make up one of these atonal-related gene families.
In neural crest cells, the atonal-related neurogenin family is particularly important for the sensory lineage (Neurogenins Are Essential for the Formation of dorsal root ganglia), while the achaete-scute homologue ash1 (Mash1) is important for aspects of autonomic neurogenesis (Mash1 Is Essential for Noradrenergic Differentiation).
Neurogenin-3 promotes pancreatic development.
Applications:Suitable for use in Immunohistochemistry, and Immunofluorescence/Immunocytochemistry.
Not recommended for use in Western Blot.
Other applications not tested.
Recommended Dilutions:Immunohistochemistry: 1:300-1:500iImmunofluorescence (IC): 1:200-1:500Optimal dilutions to be determined by the researcher.
Positive Control:Rat brain tissue
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for 12 months after receipt.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size：100ug
Host：rabbit
Source Antibody：mouse
Grade：Affinity Purified
Purity：Purified by immunoaffinity chromatography.
Form：Supplied as a liquid in PBS, pH 7.2.
Specificity：Recognizes mouse Neurogenin 3 at ~23kD. Species Crossreactivity: human and rat.
Isotype：IgG
Calc Applications Abbrev：IC IF IHC
Calc Crossreactivity：Hu Mo Rt
Immunogen：Linear peptide corresponding to aa80-93, QRRSRRKKANDRER of mouse Neurogenin 3
