84-1066-74　CIITA (Class II Trans Activator, C2TA, CIITA IV, MHC2TA, MHC class II transactivator) 100ul　C5072-61

特徴

• The transactivator CIITA regulates basal and interferon-induced expression of Major Histocompatibility Complex class II genes.
• CIITA restores expression of all MHC class II gene expression in mutant cells and corrects regulatory defects of MHC class II genes.
• Antibodies to this transactivator are useful in the study of diseases of pathological MHC class II expression.
• Antigen can be obtained from Raji cell lysates.
• Typically levels of CIITA expression are too low to detect endogenous levels of protein expression.
• Transiently transfected cells are usually employed to study this transcription factor.
• Applications:Suitable for use in ELISA, Western Blot and Immunoprecipitation.
• Other applications not tested.
• Recommended Dilution:Western Blot: 1:500Optimal dilutions to be determined by the researcher.
• Storage and Stability:May be stored at 4°C for short-term only.
• For long-term storage and to avoid repeated freezing and thawing, aliquot and add glycerol (40-50%).
• Freeze at -20°C.
• Aliquots are stable for 12 months at -20°C.
• For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
• Further dilutions can be made in assay buffer.