A subset of the tumor necrosis factor (TNF) receptor family contain a conserved intracellular motif, the death domain.
A member of this family, TRICK2, the TRAIL (TNF-related apoptosis-inducing ligand) receptor inducer of cell killing 2) is expressed in a number of cell types, and to particularly high levels in lymphocytes and spleen.
TRICK2, like DR4, is a receptor for TRAIL/APO-2L [2,3] and could inhibit TRAIL-induced killing.
Applications:Western Blot: Use at 1:500 dilution.
However, the investigator should determine the optimal dilution for a specific application such as immunohistochemistry.
Storage and Stability:May be stored at 4°C for short-term only.
For long-term storage and to avoid repeated freezing and thawing, aliquot and add glycerol (40-50%).
Store at -20°C or colder.
Aliquots are stable for at least 12 months at -20°C.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Further dilutions can be made in assay buffer.
仕様
Size:100ug
Host:rabbit
Source Antibody:human
Grade:Affinity Purified
Purity:Purified by immunoaffinity chromatography.
Form:Supplied as a liquid in PBS, pH 7.2, 0.02% sodium azide.
Specificity:Reacts with residues 380-398 (LGERLAKQKIEDHLLSSGK) of the human TRICK2 protein.