A gene, Humanin, encodes a short polypeptide and abolishes death of neuronal cells caused by multiple different types of familial Alzheimer's disease genes and by Abeta amyloid, without effect on death by Q79 or superoxide dismutase-1 mutants.
This polypeptide serves as a molecular clue for the development of new therapeutics for Alzheimer's disease targeting neuroprotection.
Applications:Suitable for use in Western Blot.
Other applications have not been tested.
Recommended Dilutions: Western Blot: 1:500 Optimal dilutions to be determined by the researcher.
Storage and Stability:May be stored at 4°C for short-term only.
For long-term storage and to avoid repeated freezing and thawing, add sterile glycerol (40-50%), aliquot and store at -20°C.
Aliquots are stable for at least 12 months at -20°C.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Further dilutions can be made in assay buffer.
仕様
Size:100ug
Host:rabbit
Source Antibody:human
Grade:Affinity Purified
Purity:Purified by immunoaffinity chromatography.
Form:Supplied as a liquid in PBS, pH 7.2, 0.02% sodium azide.
Specificity:Recognizes residues 9-24 (LLLLTSEIDLPVKRRA) of human Humanin protein.