Mycobacterium tuberculosis is the etiologic agent of tuberculosis (TB) in humans.
Humans are the only reservoir for the bacterium.
Mycobacterium bovis is the etiologic agent of TB in cows and rarely in humans.
Both cows and humans can serve as reservoirs.
Humans can also be infected by the consumption of unpasteurized milk.
This route of transmission can lead to the development of extrapulmonary TB, exemplified in history by bone infections that led to hunched backs.
Other human pathogens belonging to the Mycobacterium genus include Mycobacterium avium which causes a TB-like disease especially prevalent in AIDS patients, and Mycobacterium leprae, the causative agent of leprosy.
Mycobacterium tuberculosis is a fairly large non-motile rod-shaped bacterium distantly related to the Actinomycetes.
Many non pathogenic mycobacteria are components of the normal flora of humans, found most often in dry and oily locales.
The rods are 2-4um in length and 0.2-0.5um in width.
Mycobacterium tuberculosis is an obligate aerobe.
For this reason, in the classic case of tuberculosis, the M.TB.
complexes are always found in the well-aerated upper lobes of the lungs.
Applications:Suitable for use in ELISA, Immunocytochemistry and Gel Techniques.
Other applications not tested.
Recommended Dilutions:Optimal dilutions to be determined by the researcher.
Indirect ELISA Titer:>1:1000
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for 12 months after receipt.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size:1ml
Host:rabbit
Grade:Highly Purified
Purity:Purified IgG fraction to a purity of ≥ 95%.
Form:Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide. No stabilizing proteins have been added.
Specificity:Recognizes Mycobacterium tuberculosis. Recognizes a minimum of 2 major M. tuberculosis bands by immunoelectrophoresis (gamma & beta). It has not been cross absorbed and may react with related micro-organisms.