SDF-1b (stromal cell-derived factor-b), also known as pre-B-cell growth-stimulating factor (PBSF), is a 74-amino acid CXC chemokine originally cloned from a bone marrow stromal cell line.
Targeted deletion of SDF-1 gene resulted in defects of B-cell lymphopoiesis and bone marrow myelopoiesis in mice.
SDF-1 has been shown to be chemotactic for lymphocytes.
In addition, SDF-1 was recently reported to be a ligand for CXCR4 (LESTR/fusin), a co-receptor for HIV-1 entry into T cells.
SDF-1 binding to CXCR4 inhibits HIV-1 entry.
Applications:Suitable for use in Western Blot, Immunoprecipitation, Flow Cytometry and Immunohistochemistry.
Other applications not tested.
Recommended Dilutions:Western Blot: 1:1000Immunoprecipitation: 1:50Flow Cytometry: 1:100Immunohistochemistry: 1:100Optimal dilutions to be determined by the researcher.
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for 12 months after receipt.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size：100ug
Host：rabbit
Source Antibody：mouse
Grade：Affinity Purified
Purity：Purified by Protein A affinity chromatography
Form：Supplied as a liquid, 0.05% sodium azide
Specificity：Recognizes mouse SDF-1b. Species Crossreactivity: rat
Isotype：IgG
Calc Applications Abbrev：FC IHC IP WB
Calc Crossreactivity：Mo Rt
Immunogen：Recombinant protein corresponding to mouse SDF-1b expressed in E. coli
