LARC (liver and activation-regulated chemokine, MIP-3a, Exodus-1) is a 70-amino acid CC chemokine originally identified from human histiocytic lymphoma cell line U937 and by sequence search of the EST database.
This chemokine was mainly expressed in the liver and lung among various human tissues, and was also induced in several human cell lines.
LARC is chemotactic for lymphocytes, weakly for neutrophils at high concentration, but not for monocytes.
The LARC specific receptor has been identified as CCR6.
Applications:Suitable for use in Western Blot and Immunoprecipitation.
Other applications not tested.
Recommended Dilution:Western Blot: 1:2000Immunoprecipitation: 1:500Optimal dilutions to be determined by the researcher.
Storage and Stability:Lyophilized powder may be stored at 4°C for short-term only.
Reconstitute to nominal volume by adding sterile 40-50% glycerol and store at -20°C.
Reconstituted product is stable for 12 months at -20°C.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Further dilutions can be made in assay buffer.
仕様
Size：500ug
Host：rabbit
Source Antibody：rat
Grade：Affinity Purified
Purity：Purified by Protein A affinity chromatography.
Form：Supplied as a lyophilized powder in 0.09% sodium azide.
Specificity：Reacts with rat LARC.
Isotype：IgG
Calc Applications Abbrev：WB
Calc Crossreactivity：Rt
Immunogen：E. coli-expressed amino acid 1-70 of mature rat LARC
