IP-10 (interferon-gamma induced protein 10kD; in mouse, also called cytokine responsive gene 2, Crg- 2, or mob-1) is a highly inducible, primary response gene that belongs to the CXC chemokine superfamily.
It was first cloned in 19851.
The biological functions of IP-10 are still unclear.
Like Mig, IP-10 has no activity on neutrophils.
Its functions include stimulation of monocytes, natural killer and T-cell migration, regulation of T-cell and bone marrow progenitor maturation, modulation of adhesion molecule expression as well as inhibition of angiogenesis.
Mig and IP-10 share the same receptor, CXCR3 (2,3).
Applications:Suitable for use in Western Blot.
Other applications not tested.
Recommended Dilutions:Western Blot: 1:5000Optimal dilutions to be determined by the researcher.
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for at least 12 months.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size:100ug
Host:rabbit
Source Antibody:rat
Grade:Affinity Purified
Purity:Purified by Protein A affinity chromatography.