Ga16 is the only heterotrimeric G proteins with a restricted expression pattern in hematopoietic cells.
Differentiation of promyelocytic cells leads to decreased expression of Ga16.
This G protein is known to couple a large number of G protein-coupled receptors to PLC-B and can lead to production of the secondary messengers diacylglycerol and inositol phosphates.
Targeted deletion of Ga15, a mouse orthologue of human Ga16, causes reduced C5a receptor signaling.
Ga16 serves as a marker, in addition to CD34, for hematopoietic progenitor cells.
Applications:Suitable for use in Western Blot and Immunoprecipitation.
Other applications not tested.
Recommended Dilution:Optimal dilutions to be determined by the researcher.
Titer:Western Blot: 1:5000
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for 12 months after receipt.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size：100ug
Host：rabbit
Source Antibody：human
Grade：Affinity Purified
Purity：Purified by Protein A affinity chromatography.
Form：Supplied as a liquid, 0.05% sodium azide.
Specificity：Recognizes human Ga16 and mouse Ga15. Does not react with other G proteins.
Isotype：IgG
Calc Applications Abbrev：IP WB
Calc Crossreactivity：Hu Mo
Immunogen：E. coli-expressed human G Protein, alpha 16 (aa237-373)
