84-1063-65　CXCR4 (Fusin, LESTR, HUMSTR, C-X-C Chemokine Receptor 4, CD184) 200ug　C8350-06B

特徴

• CXCR4 (fusin) is a members in the seven-transmembrane domain G-protein-coupled chemokine receptor family.
• The full-length cDNA was isolated from a human spleen cDNA library1.
• Its ligand is chemokine stroma-derived factor (SDF).
• CXCR4 has been shown to be the co-receptor for HIV-1 binding to CD4 through the viral envelope glycoprotein gp1202.
• In other cases, CXCR4 can function as the only receptor for the interaction of HIV-2 with CD4 and host cells3.
• A mouse monoclonal antibody (12G5) to CXCR4 has been shown to inhibit HIV infectivity and HIV-induced syncytium.
• Applications:Suitable for use in Western Blot, Flow Cytometry, Immunohistochemistry and Neutralization.
• Other applications not tested.
• Recommended Dilution:Western Blot: 1:1000Flow Cytometry: 1:1000Optimal dilutions to be determined by the researcher.
• Storage and Stability:Lyophilized and reconstituted products are stable for 12 months after receipt at -20°C.
• Reconstitute with sterile ddH2O.
• Aliquot to avoid repeated freezing and thawing.
• Store at -20°C.
• For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
• Further dilutions can be made in assay buffer.