Fractalkine, also termed neurotactin, is a membrane-bound CX3C chemokine.
Rat CX3CR1, also named RBS11, was first cloned from rat brainstem, pituitary and/or spinal cord cDNA libraries.
A G-protein-coupled seven-transmembrane domain receptor, it was recently identified to serve as fractalkine receptor.
The human equivalent receptor is known as V28, which has been shown to mediate both the adhesive and migratory functions of fractalkine.
Fractalkine and CX3CR1 represent new types of leukocyte trafficking regulators.
Applications:Suitable for use in Western Blot, Flow Cytometry, Immunohistochemistry and Neutralization.
Other applications not tested.
Recommended Dilution:Western Blot: 1:1000-1:2000Flow Cytometry: 1:100-1:300Immunohistochemistry: 1:100-1:300Neutralization: calcium mobilization assaysOptimal dilutions to be determined by the researcher.
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for at least 12 months.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size：100ug
Host：rabbit
Source Antibody：rat
Grade：Affinity Purified
Purity：Purified by Protein A affinity chromatography.
Form：Supplied as a liquid, 0.05% sodium azide.
Specificity：Recognizes recombinant and natural rat CX3CR1.
Isotype：IgG
Calc Applications Abbrev：FC IHC N WB
Calc Crossreactivity：Rt
Immunogen：E. coli-expressed rat CX3CR1 amino terminal domain.
